[{"data":1,"prerenderedAt":485},["ShallowReactive",2],{"project-39142290":3},{"id":4,"name":5,"line":6,"line_source":7,"title":8,"url":9,"domain":10,"maker":11,"posted_at":12,"year":13,"points":14,"comments":15,"rank_in_year":16,"shown_in_year":17,"top":18,"tier":19,"category":20,"subcategory":21,"format":22,"keywords":23,"reception":28,"sentiment":29,"stance_mix":30,"scored_comments":35,"aspects":36,"strip":43,"post_text":46,"what":47,"said":90,"maker_in_thread":220,"shape":232,"grid":237,"attempts":445,"same_week":446,"maker_shows":385,"maker_hidden":477,"reader_version":478,"card":479},"39142290","Alzheimer's Buddy","Use Flashing Light and Sound at 40Hz","title","Show HN: Alzheimer's Buddy: Use Flashing Light and Sound at 40Hz","https:\u002F\u002Falzheimersbuddy.com\u002F","alzheimersbuddy.com","eigenvalue",1706275115,2024,96,79,862,3515,25,"notable","hardware","light and sound stimulation","web_app",[24,25,26,27],"40hz stimulation","alzheimer's","flicker light","gamma entrainment","roasted",-0.368,{"positive":31,"neutral":32,"mixed":33,"critical":34},2,21,0,23,46,{"performance":37,"idea":39,"execution":40,"docs":42},{"positive":33,"critical":38},18,{"positive":31,"critical":31},{"positive":33,"critical":41},1,{"positive":33,"critical":41},[41,44,33,44,33,41,41,41,41,41,41,33,41,41,41,41,41,41,41,44,44,41,44,41,33,44,44,45,44,44,44,44,41,44,33,44,45,44,41,41],3,5,"I recently learned about some fascinating research done at MIT for potentially treating Alzheimer’s using light and sound stimulation at 40 hertz. Nothing has been proven yet, but it seemed compelling to me, especially given the safety and simplicity of the treatment (i.e., no drugs, no electrodes, just looking at light and hearing sounds).\n\nI wanted to try it myself, but was surprised how hard it was to find something free and easy to use to generate such pulses. Which is odd because I remember some freeware DOS program I tried back in the 90s which did all this kind of stuff (anyone know wha",{"problem":48,"audience":54,"pricing":58,"motivation":62,"time_to_build":66,"stack":70,"openness":87,"stage":88,"team_size":89},{"value":49,"source":50,"evidence":51},"Hard to find a free tool to generate 40Hz light and sound pulses","maker",[52],{"id":53},"post",{"value":55,"source":50,"evidence":56},"older people wanting to try the 40Hz treatment",[57],{"id":53},{"value":59,"source":50,"evidence":60},"free",[61],{"id":53},{"value":63,"source":50,"evidence":64},"Make the 40Hz light and sound treatment accessible without waiting for FDA trials",[65],{"id":53},{"value":67,"source":50,"evidence":68},"a couple hours",[69],{"id":53},[71,75,79,83],{"value":72,"source":50,"evidence":73},"JavaScript",[74],{"id":53},{"value":76,"source":50,"evidence":77},"HTML canvas",[78],{"id":53},{"value":80,"source":50,"evidence":81},"Web Audio API",[82],{"id":53},{"value":84,"source":50,"evidence":85},"Cloudflare Pages",[86],{"id":53},"open_source","launched","solo",{"praise":91,"objections":104,"requests":154,"questions":178,"alternatives":191},[92],{"value":93,"source":94,"evidence":95},"Interesting concept and project","commenter",[96,100],{"id":97,"by":98,"text":99},"39142644","mmastrac","Cool concept and project. I don't know if browsers are capable of doing the flash reliably. I tried it out (non-epileptic and curious), and you can see that it's not a reliable…",{"id":101,"by":102,"text":103},"39142534","giantg2","Oh my, Rust vs JS. It's almost guaranteed there will be more comments about that than the actual treatment. That's awesome that you created something free. You might want to add…",[105,120,132,143],{"value":106,"source":94,"evidence":107},"Flashing damaged monitors, causing lasting flicker",[108,112,116],{"id":109,"by":110,"text":111},"39142947","adv0r","Warning: This just fucked my 2k$ 4k LG display. I ran the website 15 minutes ago and quickly closed it after 15 seconds. My screen is still flickering in the portion of the…",{"id":113,"by":114,"text":115},"39142809","roflmaostc","I'm not sure what just happened but this webpage literally damaged my monitor. There is now some flickering over the whole screen (it's not my mind, I filmed and checked my mind…",{"id":117,"by":118,"text":119},"39142665","monkey_monkey","Just a warning - running this for a few seconds has left my secondary display with an ongoing flicker which seems to be improving after 10 minutes and a reboot. [edit to add] 10…",{"value":121,"source":94,"evidence":122},"Browser timing is unreliable and 60Hz screens cannot show a true 40Hz flash",[123,124,128],{"id":97,"by":98,"text":99},{"id":125,"by":126,"text":127},"39142820","larschdk","The code effectively flashes the monitor at 30 Hz on any 60 Hz monitor (the time delta will always be 16.66 ms or more). I have tried this before and noticed a lasting effect on…",{"id":129,"by":130,"text":131},"39142515","atmanactive","Interesting, thank you for this. I'm curious, if we assume that majority of screens are at 60Hz refresh rate, how does 40Hz flashing actually outputs in real life. For a 120Hz…",{"value":133,"source":94,"evidence":134},"Seizure warning needed for flashing content",[135,139],{"id":136,"by":137,"text":138},"39142654","zackkatz","Wow, this is intense! Think twice before sampling it if you have any sensitivity to flashing lights. Might seem obvious, but apparently needs saying!",{"id":140,"by":141,"text":142},"39143261","methou","People usually put a seizure warning for flickering stimuli, for a reason.",{"value":144,"source":94,"evidence":145},"Research evidence is weak and based on mice",[146,150],{"id":147,"by":148,"text":149},"39142857","tgv","First: in mice, raised on a doxycycline-containing diet. Second: if I've understood correctly, there's no idea about what causes Alzheimer, which would reduce the significance of…",{"id":151,"by":152,"text":153},"39143125","SideburnsOfDoom","\"Flashing Light and Sound at 40Hz helps Alzheimer’s\" is an extra-ordinary claim. The research that might support the claim would be interesting, more so that Javascript that…",[155,163,174],{"value":156,"source":94,"evidence":157},"Add a clear warning about screen damage and seizures",[158,159],{"id":109,"by":110,"text":111},{"id":160,"by":161,"text":162},"39142731","cbondurant","I feel like it would be more ethically responsible for this site to put the warning it has at the top of the screen instead of the bottom. For no other reason than to be as clear…",{"value":164,"source":94,"evidence":165},"Use a microcontroller or hardware for accurate timing",[166,170],{"id":167,"by":168,"text":169},"39143152","Workaccount2","Given the problems people are having with their monitors, and the inherent issues with timing on a 60hz screen and timing on a enormous mass of abstraction... Using a…",{"id":171,"by":172,"text":173},"39175435","bobdvb","Shouldn't really need a DAC, just use the PWM output. Any $5 microcontroller should be able to do this with some reliability. Heck, the PiPico has programmable IO which could do…",{"value":175,"source":94,"evidence":176},"Verify frequency accuracy across hardware",[177],{"id":101,"by":102,"text":103},[179,184],{"value":180,"source":94,"evidence":181},"Does it work reliably on 60Hz monitors?",[182,183],{"id":129,"by":130,"text":131},{"id":125,"by":126,"text":127},{"value":185,"source":94,"evidence":186},"Why does silent mode block the audio on iPhone?",[187],{"id":188,"by":189,"text":190},"39142566","macrolime","So that's why it wasn't working. Videos and everything else will except incoming calls works in silent mode just by turning the volume up. Why is this an exception?",[192,199,209],{"value":193,"source":94,"evidence":194},"mynoise 40Hz brainwave generator",[195],{"id":196,"by":197,"text":198},"39142727","cubeanie","One of the things I've personally enjoyed using on and off in the mornings, in this 40hz space, is: https:\u002F\u002Fmynoise.net\u002FNoiseMachines\u002Fforty40HzBrainwaveGenerator.php Mynosie…",{"value":200,"source":94,"evidence":201},"Cheap signal generator with LEDs and headphones",[202,206],{"id":203,"by":204,"text":205},"39142779","throwaway4aday","Could you just buy a cheap signal generator and hook it up to some LEDs and headphones to make a hardware version of this?",{"id":207,"by":204,"text":208},"39143145","yikes! a cheapo generator on Amazon is like $10 and you can probably get them for less on AliExpress. Not sure if you'd have to amplify the signal for either LEDs or headphones…",{"value":210,"source":94,"evidence":211},"Video file played on 120Hz display",[212,216],{"id":213,"by":214,"text":215},"39156893","flir","This is funny. Just this week, I've been thinking about simulating a Dreamachine[1] in software. Isn't the obvious solution to your timing problem to distribute it as a video…",{"id":217,"by":218,"text":219},"39142844","geoffry","You can also generate a video file that does the same thing and play it back locally on a high refresh rate device (iPad Pro). Unfortunately, don't expect it to actually do…",{"comments":221,"answered":44,"key":222},8,[223,226,229],{"id":224,"text":225},"39143177","Jeez, I'm really sorry, I hadn't thought of that. It worked fine on all my screens without any issue (I tried it on 3 different ones). I just added a warning about this. Sorry…",{"id":227,"text":228},"39143308","People are saying that that if you turn it off (maybe even unplug it) for 10 minutes, it goes away. Hopefully that's the case for you.",{"id":230,"text":231},"39142555","Interesting idea. An iPhone camera now can record 60 frames per second (and much more in slow motion mode), so it seems like it wouldn’t be that hard to make something that can…",{"commenters":233,"max_depth":234,"maker_replies":221,"first_comment_mins":235,"lifespan_hours":236},56,6,27,73,[238,240,244,247,249,251,254,257,261,264,267,270,273,274,277,280,282,284,285,287,288,290,293,295,298,300,302,305,306,309,311,314,316,318,321,324,327,330,332,335,337,340,341,343,345,348,349,352,355,358,361,366,368,370,375,378,380,384,386,388,389,392,395,399,401,402,406,408,411,413,415,417,421,424,428,431,434,438,442],[109,33,41,239,110,33],"project\u002Fcritical\u002Fperformance",[241,33,44,242,243,33],"39142991","project\u002Fneutral\u002Fperformance","personalityson",[245,33,33,246,114,33],"39143006","commenter\u002Fneutral\u002Fnone",[224,33,33,248,11,41],"maker\u002Fneutral\u002Fdocs",[227,33,33,250,11,41],"maker\u002Fneutral\u002Fnone",[252,33,33,246,253,33],"39152750","dghughes",[255,33,44,242,256,33],"39143324","Tade0",[258,33,33,259,260,33],"39143372","other\u002Fneutral\u002Fnone","matei88",[262,33,33,246,263,33],"39143699","andrewjmg",[265,33,44,242,266,33],"39143516","joshspankit",[268,33,41,239,269,33],"39144873","mmh0000",[271,33,33,259,272,33],"39153709","voltaireodactyl",[97,41,41,239,98,33],[275,41,41,239,276,33],"39142803","wbobeirne",[278,41,33,246,279,33],"39164846","theon144",[147,31,41,281,148,33],"project\u002Fcritical\u002Fidea",[283,31,33,259,266,33],"39143593",[196,44,33,259,197,33],[125,286,41,239,126,33],4,[113,45,41,239,114,33],[289,45,41,239,114,33],"39142841",[291,45,33,246,292,33],"39142845","hersko",[294,45,33,246,114,33],"39142876",[296,45,41,239,297,33],"39142860","pmayrgundter",[299,45,41,239,110,33],"39142977",[301,45,33,259,260,33],"39143360",[303,45,41,239,304,33],"39144101","juggertao",[117,234,41,239,118,33],[307,234,33,246,308,33],"39142751","serf",[310,234,41,239,118,33],"39142758",[312,234,41,239,313,33],"39142802","seydor",[315,234,41,239,308,33],"39142874",[317,234,44,242,118,33],"39142910",[319,234,33,259,320,33],"39145496","mensetmanusman",[322,234,41,239,323,33],"39142967","t0mek",[325,234,41,239,326,33],"39142973","samzub",[328,234,44,242,329,33],"39143244","kkwtflz",[331,234,33,259,260,33],"39143347",[167,333,44,334,168,33],7,"project\u002Fneutral\u002Fexecution",[336,333,44,334,266,33],"39143643",[338,333,44,334,339,33],"39163585","mcapodici",[171,333,44,334,172,33],[136,221,41,342,137,33],"project\u002Fcritical\u002Fnone",[344,221,33,246,253,33],"39142679",[101,346,44,347,102,33],9,"project\u002Fneutral\u002Fdocs",[230,346,33,334,11,41],[350,346,41,239,351,33],"39142660","fstokesman",[353,346,33,354,11,41],"39142704","maker\u002Fneutral\u002Fperformance",[356,346,33,246,357,33],"39142723","aunetx",[359,346,33,246,360,33],"39142744","ladams",[362,363,44,364,365,33],"39142746",10,"project\u002Fneutral\u002Fidea","myth_drannon",[160,367,44,347,161,33],11,[213,369,44,334,214,33],12,[371,372,45,373,374,33],"39143375",13,"project\u002Fpositive\u002Fidea","keepamovin",[376,372,33,246,377,33],"39143738","swayvil",[379,372,33,246,374,33],"39143808",[381,382,44,242,383,33],"39176356",14,"mdrzn",[129,385,44,242,130,33],15,[387,385,33,354,11,41],"39142542",[188,385,44,334,189,33],[390,385,33,391,11,41],"39142670","maker\u002Fneutral\u002Fexecution",[393,385,44,242,394,33],"39142628","moconnor",[396,397,33,259,398,33],"39142780",16,"smusamashah",[151,400,41,281,152,33],17,[217,38,41,239,218,33],[403,404,33,259,405,33],"39142823",19,"nubinetwork",[203,407,44,364,204,33],20,[409,407,33,410,11,41],"39142799","project\u002Fneutral\u002Fpricing",[207,407,33,412,204,33],"other\u002Fneutral\u002Fpricing",[414,32,44,347,398,33],"39142707",[416,32,33,347,11,41],"39142720",[418,419,45,373,420,33],"39142672",22,"TimMeade",[422,34,44,334,423,33],"39143014","exceptione",[425,426,44,364,427,33],"39142643",24,"spydum",[429,18,33,259,430,33],"39143314","canadiantim",[140,432,41,433,141,33],26,"project\u002Fcritical\u002Fexecution",[435,432,33,436,437,33],"39143943","commenter\u002Fcritical\u002Fexecution","KomoD",[439,235,41,440,441,33],"39143448","project\u002Fcritical\u002Fdocs","avgcorrection",[443,444,33,259,377,33],"39143707",28,[],[447,452,457,462,467,472],{"id":448,"name":449,"points":450,"category":451},"39180953","Boardzilla",574,"languages",{"id":453,"name":454,"points":455,"category":456},"39159418","Pong 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